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Electronic whiteboard A virtual whiteboard that enable multiple collabo rators to take turns authoring and modifying hand-drawn or computer-generated graphics, highlighting points of interest on digital images, or presenting a digitized slide as part of a presentation. Entrez The search and retrieval system that integrates information from the National Center for Biotechnology (NCBI) databases. Enzymes Proteins that make chemical reactions take place faster. Eugenics Selective breeding or mating; the improvement of the human species by encouraging or permitting reproduction of only those indi viduals with genetic characteristics judged desirable. Functional genomics The study of genes, their resulting proteins, and the role played by the proteins in the body s biochemical processes. G8 The eight most industrialized nations (the Russian Federation, United States, Canada, United Kingdom, France, Germany, Italy, and Japan). GenBank An annotated collection of all publicly available DNA se quences provided by the National Institutes of Health (NIH). Gene The fundamental physical and functional unit of heredity. A gene is an ordered sequence of nucleotides located in a particular position on a particular chromosome that de nes a speci c RNA molecule. Gene chip A device that supports rapid, large-scale genetic analysis based on a large array of gene probes on a specially treated glass slide or other substrate. Thousands of experiments can be run on an array the size of a dime. Also referred to as microarray. Gene mapping Determination of the relative positions of genes on a DNA molecule and of the distance, in linkage units or physical units, between them. Gene testing Analyzing an individual s genetic material to determine pre disposition to a particular condition or to con rm a diagnosis of ge netic disease. Gene therapy A procedure aimed at replacing, manipulating, or supple menting nonfunctional or misfunctioning genes with healthy genes, typically through the use of viral vectors. Genetic code The sequence of nucleotides, coded in triplets (codons) along the mRNA, that determines the sequence of amino acids in pro tein synthesis. Genetic engineering Altering the genetic material of cells or organisms to enable them to make new substances or perform new functions. Genetic pro ling The association of particular physical and mental char acteristics with speci c genetic sequences. Genetic screening Testing a group of people to identify individuals at high risk of having or passing on a speci c genetic disorder.
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Genome project Research and technology-development effort aimed at mapping and sequencing the genome of humans, mice, and certain in sects, plants, and bacteria. Genomics The study of the genome, which includes an organism s DNA, chromosomes, and genes, usually with powerful computerbased tools. Heirloom Genetically natural. Heirloom tomatoes, popular in some trendy restaurants, supposedly come from genetically pure lines that have never been modi ed. Human Genome Project The project led by the Department of Energy (DOE) and the National Institutes of Health (NIH) to map the human genome. Immunotherapy Using the immune system to treat disease, for example, in the development of vaccines. In vitro Procedures performed outside a living organism. In vivo Studies carried out in living organisms. Internal Commercial Use Research License Agreement An agreement that allow companies to use patented or patent-pending technology for in ternal research purposes with no right to sell or utilize the technology in a commercialized material or method. International patent family Patent families for which protection has been sought in more than one country. Junk DNA Stretches of DNA that do not code for genes; most of the genome consists of so-called junk DNA which may have regulatory and other functions. Also called noncoding DNA. Knockout Containing speci c deactivated genes; a type of laboratory or ganism used to study gene function. Knockout mice and other animal models are often used to determine the effect of a gene by observing animals that lack the gene. Life extension The attempt to realize the full potential human lifespan through a variety of behavior and genetic modi cations. Material Transfer Agreement (MTA) An agreement that documents and governs the transfer of research materials to and from govern ment laboratories. Mendelian inheritance A method in which genetic traits are passed from parents to offspring, based on dominant and recessive genes. Named for the monk Gregor Mendel, who documented inheritance in pea plants. Messenger RNA (mRNA) RNA that serves as a template for protein synthesis. Microelectromechanical systems (MEMS) A technology that combines computers with tiny mechanical devices such as sensors, valves, gears, mirrors, and actuators embedded in semiconductor chips
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