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patients failing sildena l citrate alone Aging Male 2003;6:94 99 Schulman C, Destraix R, Roumeguere T Testosterone and PDE-5 inhibitors non responders J Sex Med 2004;1:(Suppl1),57 AbstrO89 McMahon C High dose Sildena l citrate as a salvage therapy for erectile dysfunction Int J Impotence Res 2002;14:(Suppl3),S89,Abstr,P511 Brisson TE, Broderick GA, Pinkstaff DM Can patients failing a PDE-5 inhibitor be rescued by another tablet : An objective assessment of 351 patients with erectile dysfunction J Urol 2005;173:(Suppl236), Abstr871 McMahon C Ef cacy and safety of daily tadala l in men with erectile dysfunction previously unresponsive to on demand tadala l J Sex Med 2004;1:292 300 Porst H Salvagetherapie mit t glicher dosierung von sildena l bei non-respondern auf on-demand therapie mit 100 mg sildena l Urologe A 2003;42: (Suppl1),S93 McMahon C Comparison of ef cacy, safety and tolerability of on-demand tadala l and daily dosed tadala l for the treatment of erectile dysfunction J Sex Med 2005;2:415 427 Montorsi F, Maga T, Strambi LF, et al Sildena l at bedtime signi cantly increases nocturnal erections: results of a placebo-controlled study Urology 200;56:906 911 Padma-Nathan H, McCullough A, Guiliano F, et al Postoperative nightly administration of sildena l citrate signi cantly improves the return of normal spontaneous erectile function after bilateral nerve-sparing radical prostatectomy J Urol 2003;169:375 Abstr1402 Schwartz EJ, Wong P, Graydon RJ Sildena l preserves intracorporeal smooth muscle after radical l retropubic prostatectomy J Urol 2004;171:771 774 Yaman , Tokath Z, Inal T, et al Effect of sildena l on nocturnal erections of potent men Int J Impotence Res 2003;15:117 121 Chen J, Piero M, Greenstein A, et al Effects of sildena l on quality of erection in healthy volunteers-NPT Rigiscan Int J Impotence Res 2003;15:(Suppl6),S58, AbstrP-O29 Ahn GJ, Kim JM, Choi SM, et al Effects of chronic treatment with a phosphodiesterase type inhibitor on erectile function in spontaneously hypertensive rats J Sex Med 2004;1:(Suppl1),63 AbstrMP7 Behr-Roussel D, Gorny D, Mevel K, et al Chronic sildena l improves erectile function and endothelium-dependent cavernosal relaxations in rats: Lack of tachyphylaxis Eur Urol 2005;47:87 91
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97 White WB, Hellstrom W, Norenberg C, et al Cardiovascular safety of vardena l in patients on antihypertensives and/or -blockers: analysis of 17 placebo-controlled trials Presented at the WorldCongress on Sexology, Montreal, 2005 98 Jackosn G, Martin E, McGing E, et al Successful withdrawal of oral long-acting nitrates to facilitate phosphodiesterase type 5 inhibitor use in stable coronary disease patients with erectile dysfunction J Sex Med 2005;2:513 516 99 Wespes E, Rammal A, Garbar C Sildena l non-reponders: hemodynamic and morphometric studies Eur Urology 2005;48:136 139 100 Atiemo HO, Szostak MJ, Sklar GN Salvage of sildena l failures referred from primary care physicians J Urol 2003;170:2356 2358 101 Jiann B-P, Yu C-C, Huang J-K Rechallenge prior sildena l non-responders Int J Impotence Res 2004; 16:64 68 102 Vardi Y, Chen Y, Shein eld O, et al A multi-center study, evaluating the effect of instruction and redosing of sildena l failures Int J Impotence Res 2002;14: (Suppl4),S15,AbstrPS-4 4 103 Hatzimouratidis K, Hatzichristou G Treatment options for erectile dysfunction in patients failing oral drug therapy EAU Update Series 2004;2:75 83 104 Cartledge J, Eardley J, Orchard C, et al Impairment of corpus cavernosal smooth muscle relaxation by glycosylated haemoglobin Eur Urol 1999;35: (Suppl2), 100,Abstr399 105 Saltzman EA, Guay AT, Jacobson J: Improvement in erectile function in men with organic erectile dysfunction by correction of elevated cholesterol levels: a clinical observation J Urol 2004;172:255 258 106 Zhang X-H, Morelli A, Luconi M, et al Testosterone regulates PDE-5 expression and in vivo responsiveness to tadala l in rat corpus cavernosum Eur Urol 2005;47:409 416 107 Aversa A, Isidori AM, Spera G, et al Androgens improve cavernous vasodilation and response to sildena l in patients with erectile dysfunction Clin Endocrinol 2003;58:632 638 108 Shabsigh R, Kaufman JM, Steidle C, Padma-Nathan H Randomized study of testosterone gel as adjunctive therapy to sildena l in hypogonadal men with erectile dysfunction who do not respond to sildena l alone J Urol 2004;172:658 663 109 Kalinchenko SY, Kozlov GL, Gontcharov NP, Katsiya GV Oral testosterone undecanoate reverses erectile dysfunction associated with diabetes mellitus in
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