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51. Gilbert, B. E.; Knight, V. (1986). Biochemistry and clinical application of ribavirin. Antimicrob. Agents Chemother. 1986, 30, 201 205. 52. Goswami, B. B.; Borek, E.; Sharma, O. K.; Fujitaki, J.; Smith, R. A. The broad spectrum antiviral agent ribavirin inhibits capping of mRNA. Biochem. Biophys. Res. Commun. 1979, 89, 830 836. 53. Crotty, S.; Maag, D.; Arnold, J. J.; Zhong, W.; Lau, J. Y. N.; Hong, Z.; Andino, R.; Cameron, C. E. The broad-spectrum antiviral ribonucleotide, ribavirin, is an RNA virus mutagen. Nat. Med. 2000, 6, 1375 1379. 54. Crotty, S.; Cameron, C. E.; Andino, R. RNA virus error catastrophe: direct molecular test by using ribavirin. Proc. Natl. Acad. Sci. U.S.A. 2001, 98, 6895 6900. 55. Ruiz-Jarabo, C. M.; Ly, C.; Domingo, E.; de la Torre, J. C. Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV). Virology 2003, 308, 37 47. 56. Tam, R. C.; Lau, J. Y. N.; Hong, Z. Mechanisms of action of ribavirin in antiviral therapies. Antiviral Chem. Chemother. 2002, 12, 261 272. 57. Wyde, P. R. Respiratory syncytial virus (RSV) disease and prospects for its control. Antiviral Res. 1998, 39, 63 79. 58. Walker, M. P.; Appleby, T. C.; Zhong, W.; Lau, J. Y. N.; Hong, Z. Hepatitis C virus therapies: current treatments, targets and future perspectives. Antiviral Chem. Chemother. 2003, 14, 1 21. 59. Jahrling P. B.; Hesse, R. A.; Eddy, G. A.; Johnson, K. M.; Callis, R. T.; Stephen, E. L. (1980). Lassa virus infection of rhesus monkeys: pathogenesis and treatment with ribavirin. J. Infect. Dis. 1980, 141, 580 589. 60. McKee, K. T.; Huggins, J. W.; Trahan, C. J.; Mahlandi, B. G. Ribavirin prophylaxis and therapy for experimental Argentine hemorrhagic fever. Antimicrob. Agents Chemother. 1988, 32, 1304 1309. 61. Kenyon, R. H.; Canonico, P. G.; Green, D. G.; Peters, C. J. Effect of ribavirin and tributylribavirin on Argentine hemorrhagic fever (Junin virus) in guinea pigs. Antimicrob. Agents Chemother. 1986, 29, 521 523. 62. Weissenbacher, M. C.; Avila, M. M.; Calello, M. A.; Merani, M. S.; McCormick, J. B.; Rodriguez, M. Effect of ribavirin and immune serum on Junin virus infected primates. Med. Microbiol. Immunol. 1986, 175, 183 186. 63. Enr a, D. A.; Briggiler, A. M.; Levis, S.; Vallejos, D.; Maiztegui, J. I.; Canonico, P. G. Tolerance and antiviral effect of ribavirin in patients with Argentine hemorrhagic fever. Antiviral Res. 1987, 7, 353 359. 64. Huggins, J. W.; Robins, R. K.; Canonico, P. G. Synergistic antiviral effects of ribavirin and the C-nucleoside analogs tiazofurin and selenazofurin against togaviruses, bunyaviruses, and arenaviruses. Antimicrob. Agents Chemother. 1984, 26, 476 480. 65. Burns, N. J. III; Barnett, B. B.; Huffman, J. H.; Dawson, M. Y.; Sidwell, R. W.; De Clercq, E.; Kende, M. A newly developed immuno uorescent assay for determining the Pichinde virus-inhibitory effects of selected nucleoside analogues. Antiviral Res. 1988, 10, 89 98. 66. Smee, D. F.; Gilbert, J.; Leonhardt, J. A.; Barnett, B. B.; Huggins, J. H.; Sidwell, R. W. Treatment of lethal Pichinde virus infections in weanling LVG/Lak hamsters with ribavirin, ribamidine, selenazofurin, and ampligen. Antiviral Res. 1993, 20, 57 70.
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67. Andrei, G.; De Clercq, E. Inhibitory effect of selected antiviral compounds on arenavirus replication in vitro. Antiviral Res. 1990, 14, 287 300. 68. Smee, D. F.; Morris, J. L. B.; Barnard, D. L.; Van Aerschot, A. Selective inhibition of arthropod-borne and arenaviruses by 30 - uoro-30 -deoxyadenosine. Antiviral Res. 1992, 18, 151 162. 69. Guillerm, G.; Guillerm, D.; Vandenplas-Vitkowski, C.; Glapski, C.; De Clercq, E. Inactivation of S-adenosyl-L-homocysteine hydrolase with novel 50 -thioadenosine derivatives. Antiviral effects. Bioorg. Med. Chem. Lett. 2003, 13, 1649 1652. 70. Martins Alho, M. A.; Sguerra, V. L.; Talarico, L. B.; Garc a, C. C.; Damonte, E. B.; D Accorso, N. Unpublished results, 2004. 71. Uckun, F. M.; Petkevich, A. S.; Vassilev, A. O.; Tibbles, H. E.; Titov, L. Stampidine prevents mortality in an experimental mouse model of viral hemorrhagic fever caused by Lassa virus. BMC Infect. Dis. 2004, 4, 1 7. 72. Burns, J. W.; Buchmeier, M. J. Protein protein interactions in lymphocytic choriomeningitis virus. Virology 1991, 163, 620 629. 73. Bruns, M.; Cihak, J.; Muller, G.; Lehmann-Grube, F. Lymphocytic choriomeningitis virus. VI. Isolation of a glycoprotein mediating neutralization. Virology 1983, 130, 247 251. 74. Parekh, B. S., Buchmeier, M. J. Proteins of lymphocytic choriomeningitis virus: antigenic topography of the viral glycoproteins. Virology 1986, 153, 168 178. 75. Borrow, P.; Oldstone, M. B. A. Characterization of lymphocytic choriomeningitis virusbinding protein (s): a candidate cellular receptor for the virus. J. Virol. 1992, 66, 7270 7281. 76. Scolaro, L. A.; Mersich, S. E.; Damonte, E. B. A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein. Arch. Virol. 1990, 111, 257 262. 77. Cao, W.; Henry, M. D.; Borrow, P.; Yamada, H.; Elder, J. H.; Ravkov, E. V.; Nichol, S. T.; Compans, R. W.; Campbell, K. P.; Oldstone, M. B. A. Identi cation of a-dystroglycan as a receptor for lymphocytic choriomeningitis virus and Lassa fever virus. Science 1998, 282, 2079 2081. 78. Henry, M. D.; and Campbell, K. P. Dystroglycan inside and out. Curr. Opin. Cell Biol. 1999, 11, 602 607. 79. Spiropoulou, C. F.; Kunz, S.; Rollin, P. E.; Campbell, K. P.; Oldstone, M. B. A. New World arenaviruses clade C, but not clade A and B viruses, utilizes a-dystroglycan as its major receptor. J. Virol. 2002, 76, 5140 5146. 80. Raiger Iustman, L. J.; Candurra, N.; Mersich, S. E. In uencia del tratamiento enzimatico sobre la interaccion virus Jun n-celulas Vero. Rev. Arg. Microbiol. 1995, 27, 28 32. 81. Schneider-Schaulies, J. Cellular receptors for viruses: links to tropism and pathogenesis. J. Gen. Virol. 2000, 81, 1413 1429. 82. Smelt, S. C.; Borrow, P.; Kunz, S.; Cao, W.; Tishon, A.; Lewicki, H.; Campbell, K. P.; Oldstone, M. B. A. Differences in af nity of binding of lymphocytic choriomeningitis virus strains to the cellular receptor a-dystroglycan correlate with viral tropism and disease kinetics. J. Virol. 2001, 75, 448 457. 83. Witvrouw, M.; Desmyter, J.; De Clercq, E. Antiviral portrait series: 4. Polysulfates as inhibitors of HIV and other enveloped viruses. Antiviral Chem. Chemother. 1994, 5, 345 359.
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